albumin - publications

Predict more albumin - ligand interactions now!

1. Angiology. 2012 Feb 19. [Epub ahead of print]

Value of Albumin-Globulin Ratio as a Predictor of All-Cause Mortality After
Non-ST Elevation Myocardial Infarction.

Azab B, Bibawy J, Harris K, Khoueiry G, Akerman M, Selim J, Khalil S, Bloom S,
McGinn JT Jr.

Department of Internal Medicine, Staten Island University Hospital, Staten Island
Island, NY, USA.

Low albumin and the albumin-globulin ratio (AGR) were associated with vascular
adverse events. Our study explores the AGR as a predictor of mortality after
non-ST-segment elevation myocardial infarction (NSTEMI). In an observational
study of 570 NSTEMI patients admitted to a tertiary center between 2004 and 2006,
patients were stratified into equal tertiles according to AGR. The primary
outcome was 4-year all-cause mortality. The 4-year mortality rates in the first,
second, and third AGR tertiles were 88 (47%) of 189, 48 (25%)of 190 , and 19
(10%) of 191, respectively (P < .0001). After adjusting for 20 confounding
variables, AGR first tertile (AGR <1.12) had a higher mortality versus second
tertile (hazard ratio [HR] 2.6, P < .001). Likewise, the AGR second tertile had
higher mortality versus the third tertile (AGR ≥1.34; HR 2.3, P = .004). The
albumin-globulin ratio is a significant independent predictor of long-term
mortality after NSTEMI in patients with normal serum albumin levels. Further
studies are needed to explain the underlying mechanisms.

PMID: 22345150 [PubMed - as supplied by publisher]