albumin - publications

Predict more albumin - ligand interactions now!


1. Diabetes Metab J. 2012 Apr;36(2):98-107. Epub 2012 Apr 17.

The roles of glycated albumin as intermediate glycation index and pathogenic
protein.

Kim KJ, Lee BW.

Severance Executive Healthcare Clinic, Yonsei University Health System, Seoul,
Korea.

The conventional glycemic indices used in management of diabetic patients
includes A1c, fructosamine, 1,5-anhydroglucitol, and glycated albumin (GA). Among
these indices, A1c is currently used as the gold standard. However, A1c cannot
reflect the glycemic change over a relatively short period of time, and its
accuracy is known to decrease when abnormalities in hemoglobin metabolism, such
as anemia, coexist. When considering these weaknesses, there have been needs for
finding a novel glycemic index for diagnosing and managing diabetes, as well as
for predicting diabetic complications properly. Recently, several studies have
suggested the potential of GA as an intermediate-term glycation index in covering
the short-term effect of treatment. Furthermore, its role as a pathogenic protein
affecting the worsening of diabetes and occurrence of diabetic complications is
receiving attention as well. Therefore, in this article, we wanted to review the
recent status of GA as a glycemic index and as a pathogenic protein.

PMCID: PMC3335903
PMID: 22540045 [PubMed - in process]