albumin - publications

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1. J Prev Med Public Health. 2012 Mar;45(2):98-104. Epub 2012 Mar 31.

The association between serum albumin levels and metabolic syndrome in a rural
population of Korea.

Cho HM, Kim HC, Lee JM, Oh SM, Choi DP, Suh I.

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul,
Korea.

OBJECTIVES: A positive association between serum albumin levels and metabolic
syndrome has been reported in observation studies, but it has not been
established in the Korean population. The purpose of this study was to evaluate
the association between serum albumin levels and the presence of metabolic
syndrome among a sample of apparently healthy Korean adults.
METHODS: This cross-sectional study analyzed data of 3189 community-dwelling
people (1189 men and 2000 women) who were aged 40 to 87 years and were living in
a rural area in Korea. Serum albumin levels were classified into quartile groups
for each sex. Metabolic syndrome was defined according to the National
Cholesterol Education Program Adult Treatment Panel III guidelines with an
adjusted waist circumference cut-off value (≥90 cm for men and ≥85 cm for women).
An independent association between serum albumin levels and metabolic syndrome
was assessed by multiple logistic regression analysis.
RESULTS: Higher serum albumin levels were associated with increased prevalence of
metabolic syndrome. The odds ratio (95% confidence interval) of the prevalence of
metabolic syndrome for the highest versus the lowest serum albumin quartiles was
2.81 (1.91 to 4.14) in men and 1.96 (1.52 to 2.52) in women, after adjusting for
age, smoking status, alcohol consumption, and physical activity. When each
metabolic abnormality was analyzed separately, higher serum albumin levels were
significantly associated with hypertriglyceridemia and hyperglycemia in both
sexes, and with abdominal obesity in men.
CONCLUSIONS: These results suggest that higher serum albumin levels are
positively associated with an increased risk of metabolic syndrome in Korean
adults.

PMCID: PMC3324721
PMID: 22509450 [PubMed - in process]