albumin - publications

Predict more albumin - ligand interactions now!

1. Analyst. 2012 Apr 25. [Epub ahead of print]

Highly selective and sensitive detection of Cu(2+) with lysine enhancing bovine
serum albumin modified-carbon dots fluorescent probe.

Liu JM, Lin LP, Wang XX, Lin SQ, Cai WL, Zhang LH, Zheng ZY.

Department of Chemistry and Environmental Science, Zhangzhou Normal College,
Zhangzhou, 363000, P.R. China.

Based on the ability of lysine (Lys) to enhance the fluorescence intensity of
bovine serum albumin modified-carbon dots (CDs-BSA) to decrease surface defects
and quench fluorescence of the CDs-BSA-Lys system in the presence of Cu(2+) under
conditions of phosphate buffer (PBS, pH = 5.0) at 45 °C for 10 min, a sensitive
Lys enhancing CDs-BSA fluorescent probe was designed. The environment-friendly,
simple, rapid, selective and sensitive fluorescent probe has been utilized to
detect Cu(2+) in hair and tap water samples and it achieved consistent results
with those obtained by inductively coupled plasma mass spectroscopy (ICP-MS). The
mechanism of the proposed assay for the detection of Cu(2+) is discussed.

PMID: 22531278 [PubMed - as supplied by publisher]