albumin - publications

Predict more albumin - ligand interactions now!


1. Arch Iran Med. 2012 Feb;15(2):85-7.

Evaluation of the pattern of human albumin utilization at a university affiliated
hospital.

Talasaz AH, Jahangard-Rafsanjani Z, Ziaie S, Fahimi F.

Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of
Medical Sciences, Tehran, Iran.fanakfahimi@yahoo.com; fahimi@nritld.ac.ir.

BACKGROUND: Albumin is a protein colloidal solution that possesses great value in
the clinic, particularly for the resuscitation of critically ill patients. It has
accounted for a high percentage of the cost in our center. This study evaluates
the appropriateness of albumin usage at Masih Daneshvari Hospital, Tehran, Iran.
METHODS: This study evaluated 69 patient charts. Data included patient
demographics, ward of admission, primary reasons for prescribing albumin, and
details of albumin use. Possible correlations between the appropriateness of
albumin usage, the number of albumin vials, and mortality rate were analyzed.
RESULTS: Albumin was prescribed appropriately in 63.8% of patients. Cardiac
surgery accounted for 37.3% of all indications. The most prevalent inappropriate
indication of albumin was for mild hypoalbuminemia and nutritional support. There
was a significant correlation between the number of used albumin vials and
mortality rate. In conclusion, the albumin use in Masih Daneshvari Hospital was
not completely in accordance with the accredited references.
CONCLUSION: Albumin is an expensive medication prescribed unnecessarily for many
patients. Using the clinical pharmacist's prepared guideline could minimize the
situations where its administration is not needed.

PMID: 22292577 [PubMed - in process]