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1. Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Jan;33(1):32-6.[Association between urinary albumin-to-creatinine ratio and prehypertension].[Article in Chinese]Zhang Q, Peng H, Ding JS, Xu YY, Chao XQ, Tian HG, Zhang YH.Department of Epidemiology, School of Public Health, Medical College of SoochowUniversity, Suzhou 215123, China; Center for Disease Control and Prevention ofJinchang District, Suzhou.OBJECTIVE: This study was operated to investigate the association between urinaryalbumin-to-creatinine ratio (UACR) and physical situations as hypertension andprehypertension among women.METHODS: Blood pressure, height, weight and waist circumference were measured andfactors such as cigarette smoking, alcohol intake, family history ofhypertension, were investigated. Blood glucose and lipid, serum uric acid,urinary albumin and urinary creatinine were tested on 1796 women aged ≥ 30 years living in the Jinchang district of Suzhou. Associations between UACR andhypertension as well as prehypertension were analyzed, by using ordinalmultinomial logistic regression models.RESULTS: The mean levels of UACR were 15.54 (7.67, 32.53), 9.01 (5.45, 18.06),7.13 (4.60, 12.50) mg/g and the rates of higher UACR were 27.57%, 13.42%, 9.61%in hypertensive, pre-hypertensive and normotensive subjects, respectively, withsignificant differences noticed among the three groups (P < 0.05). The averagesystolic blood pressure/diastolic blood pressure appeared to be 125.3/80.9,128.8/82.7, 130.8/84.0 and 135.1/85.9 mm Hg for participants with UACR in thefirst, second, third and fourth quartile, respectively. The risks ofprehypertension or hypertension increased with increasing UACR levels.Dose-response relationship was seen between UACR and risks of prehypertension or hypertension. Multivariable adjusted odds ratios (95%CI) of prehypertension orhypertension in the upper quartiles of UACR were 1.32 (1.02, 1.70), 1.72 (1.32,2.24), and 2.37 (1.80, 3.11), respectively, when compared with the lowestquartile.CONCLUSION: Elevated UACR was associated with both hypertension andprehypertension among women.PMID: 22575106 [PubMed - in process]